Medtronic Bone Drug Linked to Higher Risk of Cancer

According to information released at a conference of spinal surgeons this week, a popular bone growth product manufactured by Medtronic may increase the risk of cancer in patients, if used in high doses.

According to the New York Times, Medtronic provided the Food and Drug Administration data seeking approval to market a high-strength formulation of its Infuse bone growth product.  However, the data shows that the higher dose combination could increase cancer risks.  Based on this information, the Food and Drug Administration has rejected the high-growth formulation, which is called Amplify.

According to data that was released at the conference, there were a higher number of cancers in persons that were given the Amplify bone growth product, compared to another group of persons that was given a bone graft.  Both Amplify and Infuse have the same base ingredient, a bioengineered bone growth protein called rhBMP-2.

The increased cancer risks come from using Amplify, which is a higher-dose version of Infuse.  However, what really worries defective product attorneys is the fact that many doctors frequently use Infuse at higher-than-recommended dosage levels.  The dosage levels in Infuse, in some cases, can touch those found in Amplify.

The researchers are even more concerned about the possible risks of cancer in persons who received the higher-than-recommended doses of Infuse, and are already at a high risk of cancer.  These people include those who smoke, or suffer from any other health factors that increase their risk of cancer.  According to the findings presented at the conference, morphogenetic proteins are linked to a 2.5 times greater risk of developing cancer about one year after taking the product.  These persons also have a five times greater risk of developing cancer about three years after taking the product.

This is the first time that Infuse has been linked to health problems.  In June, the Spine Journal released a series of reports on complications involving Infuse use, including infections, bone dissolution, male sterility and leg and back pain.  Medtronic says that it is currently sponsoring research to study the safety of the Infuse bone growth product.  The results of the study will come out sometime in 2012.

What personal injury attorneys are really concerned is the widespread off-label use of Infuse.  Infuse has been approved by the Food and Drug Administration for use as part of dental procedures and in spinal fusion surgery.  However, doctors have been using it for a variety of other purposes as well, which are not approved by the Food and Drug Administration.

Content provided by The Reeves Law Group- Los Angeles personal injury lawyers. To find out additional information visit their site.

Defective Cell Phones May Cause Serious Injury

Cell phones continue to grow in popularity, as Americans increasingly rely on their cellular phone for personal and business calls. Although cell phone designs have seen advancements in past decade, some cell phones are still facing recalls for safety issues. The most common cause of cell phone injuries occur when cell phones explode or catch fire. The industry is not quick to take the blame for these defects, claiming that counterfeit batteries are the cause of cell phone explosions or fires. Others say that the problem is a result of trying to put too much power in such a small electronic device. Studies do show, however, that counterfeit batteries are less capable of preventing overheating in cell phones. This overheating leads to malfunctions and possible injury should the phone explode or catch fire.

In the incidences reported to the U.S. Consumer Product Safety Commission (CPSC), injuries occurred on the neck, face, hip and legs of most victims. The CPSC is working to create higher cell phone battery standards so that these types of injuries can be decreased in the years to come. The agency is also pushing manufacturers to issue a warning to consumers that purchasing cheap counterfeit batteries may result in injury if the phone overheats. The battery of the phone may not be at fault. Many argue that the design of the phone may be causing the problem, not allowing proper ventilation of the battery. When overheating occurs, batteries may reach temperatures near 600 degrees. In many reports of cell phone explosions or fires, victims claim that their cell phone began to make strange ticking, or “ping” noise, just before it exploded into flames. In the event that your cell phone begins to make unusual noises, do not go near it. Use another phone to call the technical support number for your phone and follow all of their instructions in order to prevent injury.

In some cases, cell phones have exploded without the owner ever having changed the battery or altered the phone in any way. If a phone is kept in a place that does not allow for ventilation, an explosion may occur. Do not keep phones in tight cases or pockets since both of these may cause the phone to become overheated. Also, avoid allowing your cell phone to come in contact with other metals such as keys or coins. Some speculate that these metals may cause the phone to short circuit and explode. If you are injured by a defective cell phone or cell phone battery, you are eligible to receive compensation for your injuries. Contacting an experienced product liability lawyer is the first step in filing a lawsuit for your injuries.

Faulty Product – Can I Claim Compensation?

Have you been injured as a result or a faulty product or has your house been damaged from a faulty product? If this is true then you have a legal and civil right to claim compensation against the manufacturer of the product.

Faulty products can be very serious, lets say you’ve bought your child a new doll of course you give it them and think nothing more of it as you would. But then your child starts choking, the eye has fell out and your child has swallowed it thinking it’s a sweetie. Eyes of dolls for children shouldn’t fall out of course they shouldn’t and so if they do the doll is faulty. A child choking on anything is serious, children have small windpipes and therefore the eye will easily get lodged in the windpipe and cause the child to choke.

It’s the same as if a kettle, toaster; microwave explodes in your home or at work. This accident could seriously burn or cause other injuries to you and others around you. Not only could you get hurt but it could also cause damage to the kitchen or area where it’s used and stored.

Claiming compensation for a faulty product may be daunting especially with large manufacturers but you shouldn’t be as The Consumer Protection Act 1987 protects consumers for incidents like this and helps bring a claim against the manufacturer for their faulty or defective product. Not only this but the Sales of Goods Act may also be helpful as it states that all products sold need to be fit for purpose, of a satisfactory quality and appear and work as they are described. So if your product is faulty or defective it isn’t a product that is in satisfactory quality and work as described.

Before you even begin to make a compensation claim contact the retailer where you bought the product and explain what’s happened, then contact trading standards who are able to offer you free advice. When you begin to make the compensation claim, make sure you still have the product in question as this serves as your evidence, also read the small print on the box or in the instructions to check that it doesn’t state this is something that may go wrong with the product. If it does state this you have very little chance of making a successful compensation claim. When you make a claim make sure you pin point exactly what happened with the product and the defect or faulty part of the product. This will help prove your claim that the product is faulty and caused you a personal injury or property damage.

If there were any witnesses of the accident whether it was a faulty product causing injury to yourself or causing property damage take names and addresses so they can be contacted later in the claim. If you took any photographs of the faulty product, your injuries the property damage this can be used as evidence. The more evidence you have the more likely your claim is to be successful. A final piece of evidence to help you make your compensation claim is to have a medical record of your injuries. You may have had to go to hospital with your injuries or just to the doctor whatever it may have been these medical records will be able to prove your injuries.

A point to remember, if the retailer or manufacturer offer you a replacement for the product that was faulty or defective that caused you injuries or your property some damage, the retailer or manufacturer will dismiss your compensation claim if you go ahead after you’ve accepted a replacement.

Jene Pedder is the Webmaster of Accident Consult who specialize in Personal Injury Compensation Claims.

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Additional Personal Injury Information for Consumers

Defective and Dangerous Products-know your Rights as a Consumer

If you received a personal injury that has caused you any pain, suffering, or lingering injuries, from a product that carried no warning label for potential injury, you do have an option for action. You have full and complete right to compensation.

Do Not Become Further Victim to the Big Companies

All too often, when people are hurt using a company’s harmful products, the company decides that it is not their fault but rather the fault of the consumer for getting hurt. Don’t let the big companies push you around. A personal injury lawyer is there to look out for your concerns only. Get one, and avoid letting the big companies fool you. A licensed attorney will understand the law — and your rights — much better than you do, and they will fight to protect both your rights and you.

Sometimes big companies that are attempting to sidestep a personal injury lawsuit will offer you a small gift certificate or money. Be aware that if you accept such offers, you give up your right to file a lawsuit against the company. Should you receive a small “gift” from a large company in an attempt at compensation, decline it and have your lawyer note these facts.

The majority of people just don’t know how to handle this situation, and that accepting such a gift from the offending company can really hurt their case.

Know the Facts About Laws

Realize that there are laws in place to protect consumers like you from buying hazardous or harmful products. Product-liability laws are some of the most effective laws in use — they help keep dangerous and defective products off the market and the buying public safe. If you are injured from any product, make sure to file a complaint and follow up with a lawsuit if necessary. You want to see similar products pulled from shelves so they don’t harm anyone else.

Control Those Emotions

It is important to keep control of your emotions so you can make effective decisions. Don’t listen to people who say that your personal injury lawsuit is frivolous. The best way to determine if you have a legitimate claim is to discuss the circumstances with a personal injury layer. If the attorney deems the claim to be valid, the lawyer may decide to represent your interests and assist you in winning the lawsuit.

If a specific type or brand of product caused you personal injury do not be afraid to get a lawyer and tell them the facts. The best way to ensure you get what you are entitled to in terms of cash or other compensation is to obtain the services of a personal injury attorney.

In cases where there was no warning label on the harmful product, most lawyers will take on your case with no retainer, due to the probability of a win. This benefits you, because you only owe legal fees if you win your case. In most cases they will be paid out of the settlement you win, or even paid by the opposition.

Don’t let big companies push you around, try to intimidate you, or try to buy you off. Fight for just compensation for your own personal injury and help protect other consumers from potentially harmful products.

Cameron Bertalone, who lives in Southern California, is the author of this article and many others on consumer legal issues. She thinks that for a Orange County Personal injury lawyer, you should try the Law Offices of Paul Ralph. They handle Orange County personal injury attorney, dog bites, and product liability issues.

Filing a Paxil Lawsuit in Texas

Filing a lawsuit in Texas is not as hard as one may think it is. If you have been the victim of a Paxil side effect or a Paxil related illness, then you should contact a Paxil attorney who can help you determine if you have legitimate lawsuit against the GlaxoSmithKline pharmaceutical company, the maker and manufacturer of Paxil. However, in the state of Texas, there are a few things that you should know about the procedures for filing your lawsuit.

As with most courts in the United States, the state of Texas has a statute of limitations law. The statute of limitations is a law set forth which defines the time period in which you can legally file a lawsuit. The statute of limitation will vary in the state of Texas depending on the type of lawsuit. So, the first thing that you will want to ask about is what the statute of limitation is regarding your particular lawsuit claim.

The Paxil lawsuit in the state of Texas is considered to be a civil case. In a civil case, there are the Defendant and the Plaintiff. The person filing the lawsuit case is the plaintiff and the other party is the defendant. The plaintiff initiates the lawsuit by contacting an attorney and the attorney will file a complaint or a petition with the court to introduce the lawsuit.

The complaint will explain all of the information regarding the lawsuit. The court will then send the complaint to the defendant and request that they enter an answer to the complaint within a specific period of time. The defendant can either agree or disagree with the complaint. The defendant also has the right to place a counter claim, which is when the defendant opens a lawsuit against the plaintiff.

After the defendant’s answer is received, then both parties will prepare for a trial. At this point in the lawsuit, all of the information, evidence, and proof are gathered. Some parties can come to an agreement outside of court to avoid a trial.

However, if the lawsuit does go to trial, then the case will be presented to a third party such as a judge. The judge will then listen to both sides and determine who is guilty and who is innocent. The judge will also determine how much compensation should be offered in regards to the lawsuit.

This is the basic process of how lawsuits function in the state of Texas. Your Paxil attorney can explain the steps involved for filing and completing your lawsuit. Each lawsuit is unique and can change. Your Paxil lawyer can explain your particular case in more detail with you. If you believe that you have a Paxil lawsuit, contact a Paxil attorney today.

Nick Johnson is lead counsel with Johnson Law Group. Johnson represents plaintiffs in many states and focuses on injury cases involving Fen-Phen and PPH, Paxil, Mesothelioma and Nursing Home Abuse. Call 1-888-311-5522 today or visit http://www.johnsonlawgroup.com

Fosamax Law Suit – What You Need to Know About Fosamax Law Suits!

This article focuses upon 4 key items related to Fosamax Law Suits:

Mechanism of Action Case Screening About the MDL State Court Litigation

Use Of Fosamax:
Bisphosphonate (others include, Zometa, Aredia, Actonel)
Used for Osteoporosis Bone Mass that is more than 2.5 std dev. Below normal.
(e.g. DEXA SCAN -2.5 or lower)
(and sometimes for Osteopenia).
Used for cancers where there is a concern of mesastisis to bones
Used for Hypercalcimia

Bone Dynamics
Structure of Bone – Think of a honey comb or an apartment complex. Hard chambers of calcium.
Bone is alive and has blood flow.
Two Processes, Three Types of Cells
Mature: Osteocyte (lives 150 days)
New: Osteoblast (an immature osteocyte)
Resorbing: Osteoclast (softens bone so old cell can be replaced)

Fosamax Do’s and Don’ts: Fosamax hardens Old Bone Fosamax does NOT make New Bone

Mechanism of Action
The Doors are Locked and Occupant is Dead
Osteoclast production inhibited
Body armor – cell chamber. Hardened Calcium
No way for dead cell to escape.
No way for new cell to enter
Blood Flow no longer supported
Bone Necrosis Occurs When a Trauma (e.g. dental work done)
Or micro can fracturing occur, since never replacing the cell walls.

ONJ – Dead Jaw: Osteneocrosis of the Jaw
Why the Jaw – Very Vascular Tissue.
Cells die inside bone & Haversion Canals Close off
Periostial Blood Flow Diminishes
Usually Trauma to Tissue on Tissue Around Bone Occurs (e.g. a routine dental procedure)
Or spontaneous ONJ – 27% of time no trauma involved!
Tissue can not get enough blood supply for nutrients to heal
Necrosis occurs and worsens problem

Spiral Fractures
Microfractures – Leading to Spiral Fracture of Femur
Small fracturing occurs naturally
Usually it is repaired by healthy living cells
In case where there are no new cells (Osteoblasts maturing into Osteocytes), there are no lives cells to repair the micro fractures
Microfractures accumulate
Resulting in a Spiral Fracture of the Femur
Studies not yet published on this

Michael Monheit, Esq. is a lawyer at Anapol Schwartz Weiss Cohan Feldman and Smalley – Fosamax Lawyers. His practice focuses upon complex pharmaceutical litigation, including Fosamax Law Suits.

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General Consumer Product Safety

More than 200,000 children go to the U.S. hospital emergency rooms annually with injuries associated with playground equipment (1).

• In 2005 over 40,000 people went to the U.S. hospital emergency room with injuries associated with riding scooters (1).

• Beware of non-CPSC complying rattles for children, often sold as party favors or as decorations, which may be small enough for a child to swallow or inhale (2).

• Strings, cords, necklaces, ribbons, and streamers can strangle infants and children (2).

• Drawstrings at the waist or bottom of jackets should extend no more than 3 inches to prevent catching in car and school bus doors or getting caught in playground equipment (2).

• If a child is under 12 months old, place the baby on his or her back and remove all soft bedding from the crib (2).

• Approximately 8,000 to 10,000 victims are treated annually in U.S. hospital emergency rooms for injuries associated with the tipover of furniture (2).

• About 6 people die each year from furniture tipovers (2).

• Each year there are 21,300 hospital emergency room treated injuries associated with baby walkers for children under 15 months of age – most of which were caused by falling down stairs (2).

• Since 1990, more than 800 deaths have occurred in spas and hot tubs. About one ¬fifth of those were drownings to children under age five. Consumers should keep a locked safety cover on the spa whenever it is not in use and keep children away unless there is constant adult supervision (2).

• Any ball with a diameter of 1.75 or less is banned for children younger than 3 years and must be labeled for children older than 3 years (2). Toys and games with small parts intended for use by children at least 3 years old but less than 6 years must be labeled (2).

• Any latex balloon, or toy or game containing a latex balloon, must be labeled (2).

• Approximately 188 people died from unintentional carbon monoxide poisoning from consumer products in 2002 (4).

• During 2004 an estimated 9,600 people were treated for fireworks-related injuries in U.S. hospital emergency departments (4).

• In 2002 an estimated 369,000 unintentional, residential structure fires in the US. led to 2,280 civilian deaths, 12,870 civilian injuries, and $5.32 billion in property loss (4).

• Cooking equipment account for the largest percentage of fires, averaging about 29.5% of total fires (4).

• There were 16 toy-related deaths involving children younger than 15 years old in 2004 (4).

• CPSC estimated that 4,900 people went to U.S. hospital emergency rooms with injuries relating to inflatable amusement rides in 2004 (4).

Works Citied:

1. U.S. Consumer Product Safety Commission. (May 18, 2006). Recalls and Product Safety News. Retrieved May 23, 2006 from http://www.cpsc.gov/

2. First Gov For Consumers. (May 9,2006). Product Safety. Retrieved May 23, 2006 from http://www.consumer.gov/productsafety.htm#Automobiles

3. Consumer Product Safety Commission. (May 25,2006). Retrieved May 25, 2006 from http://www.consumerproductsafetycommission.com/

4. Consumer Product Safety Commission. (2006). Consumer Product Safety Review.

5. Retrieved May 25, 2006 from http://www.docuticker.com/2006/04/consumer¬product-safety-review-winter.html

Sandra Worthington, Attorney at Law, obtained her law degree from Temple University in 1983. She is licensed by the Pennsylvania Bar and practices exclusively in the area of personal injury work. For more information go to The Worthington Law Group.

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